Changelog • dawnn

dawnn 2.2.0 (7 September 2026)

CRAN release: 2026-09-07

This release contains two major bugfixes, both of which can change results.

Bugfix in p-value computation. Previously, we were accidentally computing one-tailed p-values but reporting them as two-tailed. Now, we actually compute two-tailed p-values, as claimed. This will likely alter results.
Bugfix in Benjamini-Yekutieli procedure. It now steps up correctly, rather than stopping at the first p-value above its cutoff. This could alter results, but in our testing it does not seem to affect which cells Dawnn calls as in regions of DA whatsoever.

CRAN release: 2026-09-01

Documentation changes requested by CRAN: removed examples for unexported functions.

Mainly changes with a view to submitting to CRAN.

Model now hosted on Zenodo.
download_model() verifies the size and MD5 checksum of a model downloaded from the default URL, deleting it and failing if either does not match.
download_model() now saves the model to the user cache directory (tools::R_user_dir("dawnn", "cache")) by default. Other functions updated accordingly.
download_model() reports an unreachable URL with an informative message, and no longer leaves the timeout option modified if a download fails.
run_dawnn() no longer alters the global random number generator state.
The default verbosity of run_dawnn() is now 1 rather than 2, so the progress output of the underlying predict() calls is suppressed by default.
Added more sanity checks.
Vectorised p-value calculation.
Model now downloaded in binary mode, fixing corrupted downloads on Windows.
Added a vignette, a CITATION file, and package URLs.
R (>= 4.0.0) is now required, up from R (>= 3.5.0).

Simultaneously test for local and global differential abundance.
Only take single label from user (since two labels are assumed, the other need not be passed).

Fixed a bug where the alpha parameter was not being respected (the default value of 0.1 was always being used).